Provision CARES Proton Therapy Knoxville

new information alert
We are open and accepting new patients. Telehealth appointments available.


Only Proton Therapy Treatment Center in East TN

Provision CARES Proton Therapy Knoxville is the only proton therapy treatment center in East Tennessee. We feature one of the world’s most advanced cancer treatments.

More cancer patients are choosing proton therapy because it:

PRECISELY TARGETS THE TUMOR
DECREASES THE RISK OF SIDE EFFECTS
AVOIDS UNNECESSARY RADIATION

The Provision Difference in Cancer Care

Our goal is to provide unmatched cancer care by focusing on the needs of the patient. Provision’s Patient-First approach includes unique solutions to many common concerns of cancer patients:

Provision adheres to all CDC recommendations in order to protect the health and safety of our patients, employees and visitors. Learn more about the steps we are taking to ensure your cancer treatment is not delayed.


Since 2014, Provision CARES Proton Therapy Knoxville has treated over 3,000 patients from all over the world with a diversity of cancer types.  We provide the perfect combination of personalized, comprehensive patient care and leading-edge technology. Our Knoxville campus offers comprehensive services for oncology including surgery, immunotherapy, traditional radiation, clinical trials, wellness center and a clinical dietitian. Our 98% Patient Satisfaction score speaks to our excellence in patient experience and our Culture of Care.

Call today to speak with a Cancer Care Expert and learn if proton therapy is right for you.

865-770-7401

Telehealth Consultations

Speak to a physician about your diagnosis, treatment options and next steps without leaving your home. Ask one of our Cancer Care Experts about our telehealth program.

Your Care Team

The Provision CARES Proton Therapy team is comprised of leading specialists, clinicians and experts with more than 50 years of physician and imaging oncology experience.

Your Treatment Center

Provision CARES Proton Therapy Center is located in the heart of Knoxville, Tennessee, just a stone’s throw away from beautiful lakes and picturesque mountains.

Lodging and Accomodations

The Tennessee community welcomes patients, caregivers and families to the area while you visit or stay for treatment.

Contact Us

Our Cancer Care Experts are ready to help. Call us today to schedule a consultation or click the button below to request more information.

Telehealth and in-person consultations available.





Proton Ambassadors

Provision CARES Proton Therapy Knoxville formed the original Proton Ambassador Program in November 2012, with over sixty enthusiastic former proton therapy patients in the East Tennessee area, who had been treated at other proton centers domestically and globally. These former patients helped shape patient programs and many other things that would help future patients treated at Provision CARES Proton Therapy Knoxville, and the Provision CARES Cancer Network. Their genuine passion to help other patients was the driving force to the development of the program, which thrives at over 800 former proton patients today. Ambassadors volunteer to educate others, advocate for others, and most importantly, help those who have been recently diagnosed with cancer.

Learn More


Take Exit #383, Papermill Rd.
Turn right on Papermill Rd. and proceed to Weisgarber Rd. (first light)
Turn right on Weisgarber Rd. and proceed to Middlebrook Pk.
Turn left on Middlebrook Pk. and proceed to Dowell Springs Blvd. (second light)
Turn right on Dowell Springs Blvd.

Proceed to your second left.
Provision CARES Proton Therapy Center will be ahead on the right.
6450 Provision Cares Way
Knoxville, TN 37909

Take Exit #383, Papermill Rd.
Turn right on Weisgarber Rd. and proceed to Middlebrook Pk.
Turn left on Middlebrook Pk. and proceed to Dowell Springs Blvd. (second light)
Turn right on Dowell Springs Blvd. and proceed to your first left.

Proceed to your second left.
Provision CARES Proton Therapy Center will be ahead on the right.
6450 Provision Cares Way
Knoxville, TN 37909

Request Information

The Cancer Care Experts at Provision are ready to help. Contact a proton therapy treatment location near you to request more information or schedule a consultation.

Telehealth and in-person consultations available.

Partner With Us

For general information or to learn about our collaborative partnerships, future developments, ProNova proton therapy system, or investment opportunities, contact us.